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Drug-resistant TB
FDA Advisory Committee recommends accelerated approval of bedaquiline for drug-resistant TB

Bedaquiline, the first agent in a new class of TB drug, has been recommended for accelerated approval by the Anti-Infective Drugs Advisory Committee of the United States

Published
03 December 2012
By
Lesley Odendal
Drug-resistant TB
Treatment Action Group welcomes FDA review of first new tuberculosis drug in half a century

“The decision you make today is going to affect millions of people around the world,” TAG executive director Mark Harrington said today to the FDA Center for Drug Evaluation and Research at the landmark Anti-Infective Drugs Advisory Committee Meeting.

Published
29 November 2012
From
Treatment Action Group
Drug-resistant TB
New type of TB drug deemed safe by FDA

A tuberculosis drug under review by the FDA seems to work well in combination with other treatments while appearing to be "safe and well-tolerated," the agency said. Bedaquiline (Sirturo) could provide help in treating multi-drug resistant Mycobacterium tuberculosis, the FDA said in briefing documents released ahead of an advisory committee.

Published
28 November 2012
From
MedPage Today
Drug-resistant TB
How fight to tame TB made it stronger

The World Health Organization's long-standing strategy for fighting tuberculosis is showing deadly unintended consequences: By focusing for years on the easiest-to-cure patients, it helped allow TB strains to spread that are now all but untreatable by modern medicine.

Published
24 November 2012
From
Wall Street Journal
TB diagnosis
Xpert test for TB could help prevent deaths in southern Africa, but at substantial cost

A rapid test for tuberculosis (TB) could help to reduce TB deaths, improve TB treatment, and also offer reasonably good value for money if introduced in southern Africa, an area that has high rates of HIV and a type of TB that is resistant to some drugs (multi-drug resistant TB), according to a study published in this week's PLOS Medicine.

Published
21 November 2012
From
Eurekalert Inf Dis
Drug-resistant TB
MSF: Implementation of new test increases drug-resistant TB diagnosis while shortening treatment initiation time

Results from the largest multi-country implementation of the new rapid tuberculosis (TB) diagnostic test reveal an urgent need to address the growing global crisis of drug-resistant TB (DR-TB), according to the international medical humanitarian organisation Médecins Sans Frontières (MSF).

Published
15 November 2012
From
Médecins Sans Frontières press release
TB treatment
Structure discovered for promising tuberculosis drug target

Researchers at Johns Hopkins have figured out the three-dimensional shape of the protein responsible for creating unique bonds within the cell wall of the bacteria that cause tuberculosis. The bonds make the bacteria resistant to currently available drug therapies, contributing to the alarming rise of these super-bacteria throughout the world.

Published
26 October 2012
From
Eurekalert Inf Dis
Drug-resistant TB
Capacity to diagnose M/XDR-TB strengthened across Europe

WHO/Europe has established the European Tuberculosis Laboratory Initiative (ELI) to increase laboratory capacity to diagnose multidrug- and extensively drug-resistant tuberculosis (M/XDR-TB) across WHO European Region, as part of a consolidated action plan for 2011–2015.

Published
19 October 2012
From
WHO Europe
TB diagnosis
As multidrug-resistant tuberculosis continues to spread, new efforts to coordinate TB detection and treatment hold promise

TB Alliance and FIND announce collaboration to promote development of TB drugs and diagnostics.

Published
17 October 2012
From
TB Alliance
TB treatment
Curing TB in Europe is more about politics than science

Despite being considered as a disease of the past, tuberculosis (TB) kills seven people in Europe every hour and, worryingly, rates of multi drug resistant TB (MDR-TB) in the region are the highest in the world. With 81,000 MDR-TB cases in 2010 alone, the European region accounts for nearly 20 % of the global burden.

Published
11 October 2012
From
BMJ blogs
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